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Phytocannabinoids in Neurological Diseases: Could They Restore a Physiological GABAergic Transmission?

γ-Aminobutyric acid type A receptors (GABA(A)Rs) are the main inhibitory mediators in the central nervous system (CNS). GABA(A)Rs are pentameric ligand gated ion channels, and the main subunit composition is usually 2α2βγ, with various isotypes assembled within a set of 19 different subunits. The in...

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Detalles Bibliográficos
Autores principales: Cifelli, Pierangelo, Ruffolo, Gabriele, De Felice, Eleonora, Alfano, Veronica, van Vliet, Erwin Alexander, Aronica, Eleonora, Palma, Eleonora
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7038116/
https://www.ncbi.nlm.nih.gov/pubmed/31979108
http://dx.doi.org/10.3390/ijms21030723