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Increased Urinary 3-Mercaptolactate Excretion and Enhanced Passive Systemic Anaphylaxis in Mice Lacking Mercaptopyruvate Sulfurtransferase, a Model of Mercaptolactate-Cysteine Disulfiduria

Mercaptopyruvate sulfurtransferase (Mpst) and its homolog thiosulfate sulfurtransferase (Tst = rhodanese) detoxify cyanide to thiocyanate. Mpst is attracting attention as one of the four endogenous hydrogen sulfide (H(2)S)/reactive sulfur species (RSS)-producing enzymes, along with cystathionine β-s...

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Detalles Bibliográficos
Autores principales: Akahoshi, Noriyuki, Minakawa, Tatsuro, Miyashita, Masashi, Sugiyama, Uran, Saito, Chihiro, Takemoto, Rintaro, Honda, Akihiro, Kamichatani, Waka, Kamata, Shotaro, Anan, Yasumi, Ishii, Isao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7038117/
https://www.ncbi.nlm.nih.gov/pubmed/32012740
http://dx.doi.org/10.3390/ijms21030818