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TGFβ1 Regulates Human RANKL-Induced Osteoclastogenesis via Suppression of NFATc1 Expression

Osteoclasts are multinucleated giant cells responsible for bone resorption. Various mediators involved in osteoclast differentiation have been investigated as possible therapeutic targets for osteoporosis and rheumatoid arthritis (RA). Although transforming growth factor beta1 (TGFβ1) has been descr...

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Detalles Bibliográficos
Autores principales: Tokunaga, Tadahiro, Mokuda, Sho, Kohno, Hiroki, Yukawa, Kazutoshi, Kuranobu, Tatsuomi, Oi, Katsuhiro, Yoshida, Yusuke, Hirata, Shintaro, Sugiyama, Eiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7038124/
https://www.ncbi.nlm.nih.gov/pubmed/31991837
http://dx.doi.org/10.3390/ijms21030800