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Design and Synthesis of a Compound Library Exploiting 5-Methoxyleoligin as Potential Cholesterol Efflux Promoter

5-Methoxyleoligin and leoligin are natural occurring lignans derived from Edelweiss (Leontopodium nivale ssp. alpinum), displaying potent pro-angiogenic and pro-arteriogenic activity. Cholesterol efflux from macrophages is associated with reverse cholesterol transport which inhibits the development...

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Detalles Bibliográficos
Autores principales: Linder, Thomas, Geyrhofer, Sophie, Papaplioura, Eleni, Wang, Limei, Atanasov, Atanas G., Stuppner, Hermann, Dirsch, Verena M., Schnürch, Michael, Mihovilovic, Marko D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7038131/
https://www.ncbi.nlm.nih.gov/pubmed/32033108
http://dx.doi.org/10.3390/molecules25030662