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Huntington’s Disease: A Review of the Known PET Imaging Biomarkers and Targeting Radiotracers

Huntington’s disease (HD) is a fatal neurodegenerative disease caused by a CAG expansion mutation in the huntingtin gene. As a result, intranuclear inclusions of mutant huntingtin protein are formed, which damage striatal medium spiny neurons (MSNs). A review of Positron Emission Tomography (PET) st...

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Detalles Bibliográficos
Autores principales: Cybulska, Klaudia, Perk, Lars, Booij, Jan, Laverman, Peter, Rijpkema, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7038198/
https://www.ncbi.nlm.nih.gov/pubmed/31979301
http://dx.doi.org/10.3390/molecules25030482