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Huntington’s Disease: A Review of the Known PET Imaging Biomarkers and Targeting Radiotracers
Huntington’s disease (HD) is a fatal neurodegenerative disease caused by a CAG expansion mutation in the huntingtin gene. As a result, intranuclear inclusions of mutant huntingtin protein are formed, which damage striatal medium spiny neurons (MSNs). A review of Positron Emission Tomography (PET) st...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7038198/ https://www.ncbi.nlm.nih.gov/pubmed/31979301 http://dx.doi.org/10.3390/molecules25030482 |