Cargando…

Chimerization Enables Gene Synthesis and Lentiviral Delivery of Customizable TALE-Based Effectors

Designer effectors based on the DNA binding domain (DBD) of Xanthomonas transcription activator-like effectors (TALEs) are powerful sequence-specific tools with an excellent reputation for their specificity in editing the genome, transcriptome, and more recently the epigenome in multiple cellular sy...

Descripción completa

Detalles Bibliográficos
Autores principales: Fang, Yongxing, Stroukov, Wladislaw, Cathomen, Toni, Mussolino, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7038218/
https://www.ncbi.nlm.nih.gov/pubmed/31991825
http://dx.doi.org/10.3390/ijms21030795