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Discovery of Novel Inhibitors Targeting Multi-UDP-hexose Pyrophosphorylases as Anticancer Agents

To minimize treatment toxicities, recent anti-cancer research efforts have switched from broad-based chemotherapy to targeted therapy, and emerging data show that altered cellular metabolism in cancerous cells can be exploited as new venues for targeted intervention. In this study, we focused on, am...

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Detalles Bibliográficos
Autores principales: Yang, Yueqin, Vankayalapati, Hariprasad, Tang, Manshu, Zheng, Yingbo, Li, Yingri, Ma, Cong, Lai, Kent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7038226/
https://www.ncbi.nlm.nih.gov/pubmed/32028604
http://dx.doi.org/10.3390/molecules25030645