Cargando…

Engineering a CRISPR Interference System To Repress a Class 1 Integron in Escherichia coli

Microbial multidrug resistance (MDR) poses a huge threat to human health. Bacterial acquisition of MDR relies primarily on class 1 integron-involved horizontal gene transfer (HGT) of antibiotic resistance genes (ARGs). To date, no strategies other than the use of antibiotics can efficiently cope wit...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Qingyang, Zhao, Peng, Li, Lili, Zhao, Haifeng, Shi, Lei, Tian, Pingfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7038292/
https://www.ncbi.nlm.nih.gov/pubmed/31871091
http://dx.doi.org/10.1128/AAC.01789-19