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Engineering a CRISPR Interference System To Repress a Class 1 Integron in Escherichia coli

Microbial multidrug resistance (MDR) poses a huge threat to human health. Bacterial acquisition of MDR relies primarily on class 1 integron-involved horizontal gene transfer (HGT) of antibiotic resistance genes (ARGs). To date, no strategies other than the use of antibiotics can efficiently cope wit...

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Detalles Bibliográficos
Autores principales:	Li, Qingyang, Zhao, Peng, Li, Lili, Zhao, Haifeng, Shi, Lei, Tian, Pingfang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2020
Materias:	Mechanisms of Resistance
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7038292/ https://www.ncbi.nlm.nih.gov/pubmed/31871091 http://dx.doi.org/10.1128/AAC.01789-19

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