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Colon Targeting of Naringin for Enhanced Cytoprotection Against Indomethacin-Induced Colitis in Rabbits

BACKGROUND: Naringin is a promising anti-inflammatory drug against various disorders including ulcerative colitis. However, its oral bioavailability is low (8%) possibly due to cleavage at the upper gut. Consequently, colon targeting would be necessary for drug protection at the upper gut, enhanced...

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Detalles Bibliográficos
Autores principales: El Naggar, Eman Ebrahim, Mohamed, Elham Abdelmonem, Borg, Thanaa Mohamed, El-Sheakh, Ahmed Ramadan, Hamed, Mohammed Fawzy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7038417/
https://www.ncbi.nlm.nih.gov/pubmed/32109993
http://dx.doi.org/10.2147/DDDT.S218357