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Thalidomide attenuates the hyporesponsiveness of isolated atria to chronotropic stimulation in BDL rats: The involvement of TNF-α, IL-6 inhibition, and SOCS1 activation

OBJECTIVE(S): Cirrhotic cardiomyopathy is a complication of uncured cirrhosis which is associated with hyporesponsiveness of the heart to sympathetic stimulation. The enhancement of portal pressure, nitric oxide (NO) level, pro-inflammatory mediators and down-regulation of Suppressor of Cytokine Sig...

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Detalles Bibliográficos
Autores principales: Hosseini-Chegeni, Ali, Jazaeri, Farahnaz, Yousefi-Ahmadipour, Aliakbar, Heidari, Mansour, Abdollahie, Alireza, Dehpour, Ahmad Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7038422/
https://www.ncbi.nlm.nih.gov/pubmed/32128089
http://dx.doi.org/10.22038/ijbms.2019.32256.7742