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Akt inhibitor deguelin aggravates inflammation and fibrosis in myocarditis
OBJECTIVE(S): Myocarditis is characterized by inflammatory cell infiltration in myocardial stroma. Attenuation of tumor necrosis factor (TNF)-α and interleukin (IL)-1β is a reliable mark for improving the prognosis. Protein kinase B (Akt) plays an important role in the development and progression of...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mashhad University of Medical Sciences
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7038425/ https://www.ncbi.nlm.nih.gov/pubmed/32128091 http://dx.doi.org/10.22038/ijbms.2019.35518.8473 |