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Eupafolin ameliorates lipopolysaccharide-induced cardiomyocyte autophagy via PI3K/AKT/mTOR signaling pathway

OBJECTIVE(S): Eupafolin, a major active component of Eupatorium perfoliatum L., has anti-inflammatory and anti-oxidant properties. Lipopolysaccharide (LPS) is responsible for myocardial depression. A line of evidences revealed that LPS induces autophagy in cardiomyocytes injury. This study aims to e...

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Detalles Bibliográficos
Autores principales: Gao, Yan, Zhang, Yi, Fan, Yangyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7038429/
https://www.ncbi.nlm.nih.gov/pubmed/32128100
http://dx.doi.org/10.22038/ijbms.2019.37748.8977