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Conversion of mesenchymal stem cells into a canine hepatocyte-like cells by Foxa1 and Hnf4a

INTRODUCTION: Hepatocytes, which account for the majority of liver tissue, are derived from the endoderm and become hepatocytes via differentiation of hepatic progenitor cells. Induced hepatocyte-like (iHep) cells and artificial liver tissues are expected to become useful, efficient therapies for se...

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Detalles Bibliográficos
Autores principales: Nitta, Suguru, Kusakari, Yuto, Yamada, Yoko, Kubo, Takeaki, Neo, Sakurako, Igarashi, Hirotaka, Hisasue, Masaharu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society for Regenerative Medicine 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7038439/
https://www.ncbi.nlm.nih.gov/pubmed/32123700
http://dx.doi.org/10.1016/j.reth.2020.01.003