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Hierarchical structural component model for pathway analysis of common variants

BACKGROUND: Genome-wide association studies (GWAS) have been widely used to identify phenotype-related genetic variants using many statistical methods, such as logistic and linear regression. However, GWAS-identified SNPs, as identified with stringent statistical significance, explain just a small p...

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Detalles Bibliográficos
Autores principales: Jiang, Nan, Lee, Sungyoung, Park, Taesung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7038534/
https://www.ncbi.nlm.nih.gov/pubmed/32093692
http://dx.doi.org/10.1186/s12920-019-0650-0