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Molecular pathways driving omeprazole nephrotoxicity

Omeprazole, a proton pump inhibitor used to treat peptic ulcer and gastroesophageal reflux disease, has been associated to chronic kidney disease and acute interstitial nephritis. However, whether omeprazole is toxic to renal cells is unknown. Omeprazole has a lethal effect over some cancer cells, a...

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Detalles Bibliográficos
Autores principales: Fontecha-Barriuso, Miguel, Martín-Sanchez, Diego, Martinez-Moreno, Julio M., Cardenas-Villacres, Daniela, Carrasco, Susana, Sanchez-Niño, Maria D., Ruiz-Ortega, Marta, Ortiz, Alberto, Sanz, Ana B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7038587/
https://www.ncbi.nlm.nih.gov/pubmed/32092686
http://dx.doi.org/10.1016/j.redox.2020.101464