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TRAF1 suppresses antifungal immunity through CXCL1-mediated neutrophil recruitment during Candida albicans intradermal infection

BACKGROUND: Candida albicans is the most common opportunistic human fungal pathogen. The chemokine ligand CXCL1 plays a protective role in fungal infection through the recruitment of neutrophils. TRAF1 (tumor necrosis factor-associated factor 1) can be highly induced by proinflammatory stimuli such...

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Detalles Bibliográficos
Autores principales: Bai, Wenjuan, Wang, Qingqing, Deng, Zihou, Li, Tiantian, Xiao, Hui, Wu, Zhiyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7038620/
https://www.ncbi.nlm.nih.gov/pubmed/32093731
http://dx.doi.org/10.1186/s12964-020-00532-x