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CD4(+)CD38(+) central memory T cells contribute to HIV persistence in HIV-infected individuals on long-term ART

BACKGROUND: Despite the effective antiretroviral treatment (ART) of HIV-infected individuals, HIV persists in a small pool. Central memory CD4(+) T cells (Tcm) make a major contribution to HIV persistence. We found that unlike HLA-DR, CD38 is highly expressed on the Tcm of HIV-infected subjects rece...

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Detalles Bibliográficos
Autores principales: Song, Cheng-Bo, Zhang, Le-Le, Wu, Xian, Fu, Ya-Jing, Jiang, Yong-Jun, Shang, Hong, Zhang, Zi-Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7038621/
https://www.ncbi.nlm.nih.gov/pubmed/32093678
http://dx.doi.org/10.1186/s12967-020-02245-8