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A Bayesian Framework for Inferring the Influence of Sequence Context on Point Mutations
The probability of point mutations is expected to be highly influenced by the flanking nucleotides that surround them, known as the sequence context. This phenomenon may be mainly attributed to the enzyme that modifies or mutates the genetic material, because most enzymes tend to have specific seque...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7038660/ https://www.ncbi.nlm.nih.gov/pubmed/31651955 http://dx.doi.org/10.1093/molbev/msz248 |