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Lipid-Based Gliclazide Nanoparticles for Treatment of Diabetes: Formulation, Pharmacokinetics, Pharmacodynamics and Subacute Toxicity Study

INTRODUCTION: Solid lipid nanoparticles (SLNs) are considered a promising system in enhancing the oral bioavailability of poorly water-soluble drugs; owing to their intrinsic ability to increase the solubility together with protecting the incorporated drugs from extensive metabolism. OBJECTIVE: Expl...

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Detalles Bibliográficos
Autores principales: Nazief, Alaa Mohamed, Hassaan, Passainte Saber, Khalifa, Hoda Mahmoud, Sokar, Magda Samir, El-Kamel, Amal Hassan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7038779/
https://www.ncbi.nlm.nih.gov/pubmed/32110012
http://dx.doi.org/10.2147/IJN.S235290