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MicroRNA-22 enhances radiosensitivity in cervical cancer cell lines via direct inhibition of c-Myc binding protein, and the subsequent reduction in hTERT expression

MicroRNAs (miRs) influence the expression of their target genes post-transcriptionally and serve an important role in multiple cellular processes. The downregulation of miR-22 is associated with a poor prognosis in cervical cancer. However, the mechanisms underlying miR-22-mediated gene regulation a...

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Detalles Bibliográficos
Autores principales: Nakamura, Mayumi, Hayashi, Masami, Konishi, Hiromi, Nunode, Misa, Ashihara, Keisuke, Sasaki, Hiroshi, Terai, Yoshito, Ohmichi, Masahide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7038919/
https://www.ncbi.nlm.nih.gov/pubmed/32194719
http://dx.doi.org/10.3892/ol.2020.11344