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A chromatin scaffold for DNA damage recognition: how histone methyltransferases prime nucleosomes for repair of ultraviolet light-induced lesions

The excision of mutagenic DNA adducts by the nucleotide excision repair (NER) pathway is essential for genome stability, which is key to avoiding genetic diseases, premature aging, cancer and neurologic disorders. Due to the need to process an extraordinarily high damage density embedded in the nucl...

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Detalles Bibliográficos
Autores principales: Gsell, Corina, Richly, Holger, Coin, Frédéric, Naegeli, Hanspeter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7038933/
https://www.ncbi.nlm.nih.gov/pubmed/31930303
http://dx.doi.org/10.1093/nar/gkz1229