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Modulated control of DNA supercoiling balance by the DNA-wrapping domain of bacterial gyrase

Negative supercoiling by DNA gyrase is essential for maintaining chromosomal compaction, transcriptional programming, and genetic integrity in bacteria. Questions remain as to how gyrases from different species have evolved profound differences in their kinetics, efficiency, and extent of negative s...

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Detalles Bibliográficos
Autores principales: Hobson, Matthew J, Bryant, Zev, Berger, James M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7038939/
https://www.ncbi.nlm.nih.gov/pubmed/31950157
http://dx.doi.org/10.1093/nar/gkz1230