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Modulated control of DNA supercoiling balance by the DNA-wrapping domain of bacterial gyrase
Negative supercoiling by DNA gyrase is essential for maintaining chromosomal compaction, transcriptional programming, and genetic integrity in bacteria. Questions remain as to how gyrases from different species have evolved profound differences in their kinetics, efficiency, and extent of negative s...
Autores principales: | Hobson, Matthew J, Bryant, Zev, Berger, James M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7038939/ https://www.ncbi.nlm.nih.gov/pubmed/31950157 http://dx.doi.org/10.1093/nar/gkz1230 |
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