Strong suppression of gene conversion with increasing DNA double-strand break load delimited by 53BP1 and RAD52

In vertebrates, genomic DNA double-strand breaks (DSBs) are removed by non-homologous end-joining processes: classical non-homologous end-joining (c-NHEJ) and alternative end-joining (alt-EJ); or by homology-dependent processes: gene-conversion (GC) and single-strand annealing (SSA). Surprisingly, t...

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Detalles Bibliográficos
Autores principales: Mladenov, Emil, Staudt, Christian, Soni, Aashish, Murmann-Konda, Tamara, Siemann-Loekes, Maria, Iliakis, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7038941/
https://www.ncbi.nlm.nih.gov/pubmed/31832684
http://dx.doi.org/10.1093/nar/gkz1167

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7038941/
https://www.ncbi.nlm.nih.gov/pubmed/31832684
http://dx.doi.org/10.1093/nar/gkz1167

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