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In vitro selection of l-DNA aptamers that bind a structured d-RNA molecule
The development of structure-specific RNA binding reagents remains a central challenge in RNA biochemistry and drug discovery. Previously, we showed in vitro selection techniques could be used to evolve l-RNA aptamers that bind tightly to structured d-RNAs. However, whether similar RNA-binding prope...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7038948/ https://www.ncbi.nlm.nih.gov/pubmed/31950158 http://dx.doi.org/10.1093/nar/gkz1236 |