Highly specific enrichment of rare nucleic acid fractions using Thermus thermophilus argonaute with applications in cancer diagnostics

Detection of disease-associated, cell-free nucleic acids in body fluids enables early diagnostics, genotyping and personalized therapy, but is challenged by the low concentrations of clinically significant nucleic acids and their sequence homology with abundant wild-type nucleic acids. We describe a...

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Detalles Bibliográficos
Autores principales: Song, Jinzhao, Hegge, Jorrit W, Mauk, Michael G, Chen, Junman, Till, Jacob E, Bhagwat, Neha, Azink, Lotte T, Peng, Jing, Sen, Moen, Mays, Jazmine, Carpenter, Erica L, van der Oost, John, Bau, Haim H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7038991/
https://www.ncbi.nlm.nih.gov/pubmed/31828328
http://dx.doi.org/10.1093/nar/gkz1165

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7038991/
https://www.ncbi.nlm.nih.gov/pubmed/31828328
http://dx.doi.org/10.1093/nar/gkz1165

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