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Identification of altered biological processes in heterogeneous RNA-sequencing data by discretization of expression profiles

Heterogeneity is a fundamental feature of complex phenotypes. So far, genomic screenings have profiled thousands of samples providing insights into the transcriptome of the cell. However, disentangling the heterogeneity of these transcriptomic Big Data to identify defective biological processes rema...

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Detalles Bibliográficos
Autores principales: Lauria, Andrea, Peirone, Serena, Giudice, Marco Del, Priante, Francesca, Rajan, Prabhakar, Caselle, Michele, Oliviero, Salvatore, Cereda, Matteo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7038995/
https://www.ncbi.nlm.nih.gov/pubmed/31889184
http://dx.doi.org/10.1093/nar/gkz1208