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Identification of altered biological processes in heterogeneous RNA-sequencing data by discretization of expression profiles
Heterogeneity is a fundamental feature of complex phenotypes. So far, genomic screenings have profiled thousands of samples providing insights into the transcriptome of the cell. However, disentangling the heterogeneity of these transcriptomic Big Data to identify defective biological processes rema...
Autores principales: | Lauria, Andrea, Peirone, Serena, Giudice, Marco Del, Priante, Francesca, Rajan, Prabhakar, Caselle, Michele, Oliviero, Salvatore, Cereda, Matteo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7038995/ https://www.ncbi.nlm.nih.gov/pubmed/31889184 http://dx.doi.org/10.1093/nar/gkz1208 |
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