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iFLinkC: an iterative functional linker cloning strategy for the combinatorial assembly and recombination of linker peptides with functional domains

Recent years have witnessed increasing efforts to engineer artificial biological functions through recombination of modular-organized toolboxes of protein scaffolds and parts. A critical, yet frequently neglected aspect concerns the identity of peptide linkers or spacers connecting individual domain...

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Detalles Bibliográficos
Autores principales: Gräwe, Alexander, Ranglack, Jan, Weyrich, Anastasia, Stein, Viktor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7039005/
https://www.ncbi.nlm.nih.gov/pubmed/31925441
http://dx.doi.org/10.1093/nar/gkz1210