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Frequency of somatic mutations in TERT promoter, TP53 and CTNNB1 genes in patients with hepatocellular carcinoma from Southern Italy

Somatic mutations in the TERT promoter and in the TP53 and CTNNB1 genes are considered drivers for hepatocellular carcinoma (HCC) development. They show variable frequencies in different geographic areas, possibly depending on liver disease etiology and environmental factors. TP53, CTNNB1 and TERT g...

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Detalles Bibliográficos
Autores principales: Lombardo, Daniele, Saitta, Carlo, Giosa, Domenico, Di Tocco, Francesca Casuscelli, Musolino, Cristina, Caminiti, Giuseppe, Chines, Valeria, Franzè, Maria Stella, Alibrandi, Angela, Navarra, Giuseppe, Raimondo, Giovanni, Pollicino, Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7039085/
https://www.ncbi.nlm.nih.gov/pubmed/32194736
http://dx.doi.org/10.3892/ol.2020.11332