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THBS2, a microRNA-744-5p target, modulates MMP9 expression through CUX1 in pancreatic neuroendocrine tumors

The underlying molecular mechanisms of pancreatic neuroendocrine tumor (pNET) development have not yet been clearly identified. The present study revealed that thrombospondin 2 (THBS2) was downregulated in pNET tissues and cells. Forced expression of THBS2 inhibited the proliferation and migration o...

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Detalles Bibliográficos
Autores principales: Jiao, Heng, Zeng, Lingxiao, Zhang, Jianpeng, Yang, Shengsheng, Lou, Wenhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7039111/
https://www.ncbi.nlm.nih.gov/pubmed/32194660
http://dx.doi.org/10.3892/ol.2020.11273