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Role of Bcl-2 on drug resistance in breast cancer polyploidy-induced spindle poisons
Spindle poisons are chemotherapeutic drugs used in the treatment of malignant tumors; however, numerous patients develop resistance following chemotherapy. The present study aimed to induce polyploidy in breast cancer cells using the spindle poison nocodazole to investigate the mechanism of polyploi...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
D.A. Spandidos
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7039128/ https://www.ncbi.nlm.nih.gov/pubmed/32194662 http://dx.doi.org/10.3892/ol.2020.11256 |