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PTPN11 hypomethylation is associated with gastric cancer progression

Protein tyrosine phosphatase non-receptor type 11 (PTPN11) encodes the tyrosine phosphatase SHP-2 that is overexpressed in gastric cancer (GC). In the present study, the association of PTPN11 methylation levels with the incidence of GC and its correlation with SHP-2 overexpression were investigated....

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Detalles Bibliográficos
Autores principales: Xu, Lele, Zhou, Cong, Pan, Ranran, Tang, Junjian, Wang, Jinzhi, Li, Bin, Huang, Tianyi, Duan, Shiwei, Xu, Chunfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7039138/
https://www.ncbi.nlm.nih.gov/pubmed/32194661
http://dx.doi.org/10.3892/ol.2020.11250