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FBW7 in hematological tumors

F-box and WD repeat domain-containing protein 7 (FBW7), also known as FBXW7, AGO or hCDC4, is an F-box protein with seven tandem WD40 repeats. FBW7 is a key substrate recognition subunit of the Skp1-Cul1-F-box-protein E3 ubiquitin ligase. FBW7 targets for ubiquitination and destruction of numerous c...

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Detalles Bibliográficos
Autores principales: Zhu, Qiaojuan, Hu, Linjun, Guo, Yang, Xiao, Zunqiang, Xu, Qiuran, Tong, Xiangmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7039162/
https://www.ncbi.nlm.nih.gov/pubmed/32194657
http://dx.doi.org/10.3892/ol.2020.11264