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WBP11 is required for splicing the TUBGCP6 pre-mRNA to promote centriole duplication
Centriole duplication occurs once in each cell cycle to maintain centrosome number. A previous genome-wide screen revealed that depletion of 14 RNA splicing factors leads to a specific defect in centriole duplication, but the cause of this deficit remains unknown. Here, we identified an additional p...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7039186/ https://www.ncbi.nlm.nih.gov/pubmed/31874114 http://dx.doi.org/10.1083/jcb.201904203 |