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WBP11 is required for splicing the TUBGCP6 pre-mRNA to promote centriole duplication

Centriole duplication occurs once in each cell cycle to maintain centrosome number. A previous genome-wide screen revealed that depletion of 14 RNA splicing factors leads to a specific defect in centriole duplication, but the cause of this deficit remains unknown. Here, we identified an additional p...

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Detalles Bibliográficos
Autores principales:	Park, Elizabeth M., Scott, Phillip M., Clutario, Kevin, Cassidy, Katelyn B., Zhan, Kevin, Gerber, Scott A., Holland, Andrew J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2019
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7039186/ https://www.ncbi.nlm.nih.gov/pubmed/31874114 http://dx.doi.org/10.1083/jcb.201904203

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