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ORP5 localizes to ER–lipid droplet contacts and regulates the level of PI(4)P on lipid droplets

Lipid droplets (LDs) are evolutionarily conserved organelles that play important roles in cellular metabolism. Each LD is enclosed by a monolayer of phospholipids, distinct from bilayer membranes. During LD biogenesis and growth, this monolayer of lipids expands by acquiring phospholipids from the e...

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Detalles Bibliográficos
Autores principales: Du, Ximing, Zhou, Linkang, Aw, Yvette Celine, Mak, Hoi Yin, Xu, Yanqing, Rae, James, Wang, Wenmin, Zadoorian, Armella, Hancock, Sarah E., Osborne, Brenna, Chen, Xiang, Wu, Jia-Wei, Turner, Nigel, Parton, Robert G., Li, Peng, Yang, Hongyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7039201/
https://www.ncbi.nlm.nih.gov/pubmed/31653673
http://dx.doi.org/10.1083/jcb.201905162