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Mechanical Postconditioning Promotes Glucose Metabolism and AMPK Activity in Parallel with Improved Post-Ischemic Recovery in an Isolated Rat Heart Model of Donation after Circulatory Death

Donation after circulatory death (DCD) could improve donor heart availability; however, warm ischemia-reperfusion injury raises concerns about graft quality. Mechanical postconditioning (MPC) may limit injury, but mechanisms remain incompletely characterized. Therefore, we investigated the roles of...

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Detalles Bibliográficos
Autores principales: Arnold, Maria, Méndez-Carmona, Natalia, Gulac, Patrik, Wyss, Rahel K, Rutishauser, Nina, Segiser, Adrian, Carrel, Thierry, Longnus, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7039237/
https://www.ncbi.nlm.nih.gov/pubmed/32024002
http://dx.doi.org/10.3390/ijms21030964