HP1 reshapes the nucleosome core to promote phase separation of heterochromatin

Heterochromatin impacts genome function at multiple scales. It enables heritable gene repression, maintains chromosome integrity and provides mechanical rigidity to the nucleus(1,2). It has been proposed that these diverse functions arise in part from compaction of the underlying chromatin. A major...

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Detalles Bibliográficos
Autores principales: Sanulli, S., Trnka, MJ., Dharmarajan, V., Tibble, RW., Pascal, BD., Burlingame, AL., Griffin, PR., Gross, JD., Narlikar, GJ.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7039410/
https://www.ncbi.nlm.nih.gov/pubmed/31618757
http://dx.doi.org/10.1038/s41586-019-1669-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7039410/
https://www.ncbi.nlm.nih.gov/pubmed/31618757
http://dx.doi.org/10.1038/s41586-019-1669-2

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