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HP1 reshapes the nucleosome core to promote phase separation of heterochromatin
Heterochromatin impacts genome function at multiple scales. It enables heritable gene repression, maintains chromosome integrity and provides mechanical rigidity to the nucleus(1,2). It has been proposed that these diverse functions arise in part from compaction of the underlying chromatin. A major...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7039410/ https://www.ncbi.nlm.nih.gov/pubmed/31618757 http://dx.doi.org/10.1038/s41586-019-1669-2 |