Protein secondary structure determines the temporal relationship between folding and disulfide formation

How and when disulfide bonds form in proteins relative to the stage of their folding is a fundamental question in cell biology. Two models describe this relationship: the folded precursor model, in which a nascent structure forms before disulfides do, and the quasi-stochastic model, where disulfides...

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Detalles Bibliográficos
Autores principales: Robinson, Philip J., Kanemura, Shingo, Cao, Xiaofei, Bulleid, Neil J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Protein Structure and Folding
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7039548/
https://www.ncbi.nlm.nih.gov/pubmed/31953323
http://dx.doi.org/10.1074/jbc.RA119.011983

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7039548/
https://www.ncbi.nlm.nih.gov/pubmed/31953323
http://dx.doi.org/10.1074/jbc.RA119.011983

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