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Protein secondary structure determines the temporal relationship between folding and disulfide formation
How and when disulfide bonds form in proteins relative to the stage of their folding is a fundamental question in cell biology. Two models describe this relationship: the folded precursor model, in which a nascent structure forms before disulfides do, and the quasi-stochastic model, where disulfides...
Autores principales: | Robinson, Philip J., Kanemura, Shingo, Cao, Xiaofei, Bulleid, Neil J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7039548/ https://www.ncbi.nlm.nih.gov/pubmed/31953323 http://dx.doi.org/10.1074/jbc.RA119.011983 |
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