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Loss of voltage-gated proton channel Hv1 leads to diet-induced obesity in mice

OBJECTIVE: The voltage-gated proton channel Hv1 has been proposed to mediate NADPH oxidase (NOX) function by regulating intracellular pH during respiratory bursts. In our previous work, we showed that Hv1 is expressed in pancreatic β cells and positively regulates insulin secretion. Here, we investi...

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Detalles Bibliográficos
Autores principales: Pang, Huimin, Li, Jinwen, Du, Hongyan, Gao, Yingtang, Lv, Jili, Liu, Yanxia, Li, Shu Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7039614/
https://www.ncbi.nlm.nih.gov/pubmed/32049639
http://dx.doi.org/10.1136/bmjdrc-2019-000951