Cargando…

COTI-2 induces cell apoptosis in pediatric acute lymphoblastic leukemia via upregulation of miR-203

COTI-2 is a third-generation thiosemicarbazone, which is effective against a diverse group of human cancer cell lines at nanomolar concentrations. COTI-2 also showed superior activity against tumor cells, in vitro and in vivo. As a high efficacy and low toxicity agent, it currently candidates in a p...

Descripción completa

Detalles Bibliográficos
Autores principales: Guo, Yingmeng, Zhu, Xia, Sun, Xuerong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7039633/
https://www.ncbi.nlm.nih.gov/pubmed/32063077
http://dx.doi.org/10.1080/21655979.2020.1729927