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COTI-2 induces cell apoptosis in pediatric acute lymphoblastic leukemia via upregulation of miR-203
COTI-2 is a third-generation thiosemicarbazone, which is effective against a diverse group of human cancer cell lines at nanomolar concentrations. COTI-2 also showed superior activity against tumor cells, in vitro and in vivo. As a high efficacy and low toxicity agent, it currently candidates in a p...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Taylor & Francis
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7039633/ https://www.ncbi.nlm.nih.gov/pubmed/32063077 http://dx.doi.org/10.1080/21655979.2020.1729927 |