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Activating Sirt1 by resveratrol suppresses Nav1.7 expression in DRG through miR-182 and alleviates neuropathic pain in rats

Neuropathic pain is clinically unsatisfactorily treated because of unclear mechanisms. The present study aims to explore the concrete mechanisms underlying the alleviation of resveratrol-activated silent information regulator 1 (Sirt1) to chronic constriction injury (CCI)-induced neuropathic pain. C...

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Detalles Bibliográficos
Autores principales: Jia, Qianqian, Dong, Wenze, Zhang, Liwei, Yang, Xiaochun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7039643/
https://www.ncbi.nlm.nih.gov/pubmed/32089065
http://dx.doi.org/10.1080/19336950.2020.1732003