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Impact of thrombocytes, on bacterial growth and antimicrobial activity of selected antibiotics

In vitro pharmacodynamic models are used to optimize in vivo dosing regimens in antimicrobial drug development. One limiting factor of such models is the lack of host factors such as corpuscular blood components as erythrocytes which have already been shown to impact activity of antibiotics and/or g...

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Detalles Bibliográficos
Autores principales: Nussbaumer-Pröll, Alina Karoline, Eberl, Sabine, Reiter, Birgit, Stimpfl, Thomas, Jäger, Walter, Poschner, Stefan, Zeitlinger, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7039845/
https://www.ncbi.nlm.nih.gov/pubmed/31788739
http://dx.doi.org/10.1007/s10096-019-03762-1