Discovery of suppressors of CRMP2 phosphorylation reveals compounds that mimic the behavioral effects of lithium on amphetamine-induced hyperlocomotion

The effective treatment of bipolar disorder (BD) represents a significant unmet medical need. Although lithium remains a mainstay of treatment for BD, limited knowledge regarding how it modulates affective behavior has proven an obstacle to discovering more effective mood stabilizers with fewer adve...

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Detalles Bibliográficos
Autores principales: Zhao, Wen-Ning, Tobe, Brian T. D., Udeshi, Namrata D., Xuan, Lucius L., Pernia, Cameron D., Zolg, Daniel P., Roberts, Amanda J., Mani, Deepak, Blumenthal, Sarah R., Kurtser, Iren, Patnaik, Debasis, Gaisina, Irina, Bishop, Joshua, Sheridan, Steven D., Lalonde, Jasmin, Carr, Steven A., Snyder, Evan Y., Haggarty, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7039883/
https://www.ncbi.nlm.nih.gov/pubmed/32094324
http://dx.doi.org/10.1038/s41398-020-0753-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7039883/
https://www.ncbi.nlm.nih.gov/pubmed/32094324
http://dx.doi.org/10.1038/s41398-020-0753-6

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