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Discovery of suppressors of CRMP2 phosphorylation reveals compounds that mimic the behavioral effects of lithium on amphetamine-induced hyperlocomotion
The effective treatment of bipolar disorder (BD) represents a significant unmet medical need. Although lithium remains a mainstay of treatment for BD, limited knowledge regarding how it modulates affective behavior has proven an obstacle to discovering more effective mood stabilizers with fewer adve...
Autores principales: | Zhao, Wen-Ning, Tobe, Brian T. D., Udeshi, Namrata D., Xuan, Lucius L., Pernia, Cameron D., Zolg, Daniel P., Roberts, Amanda J., Mani, Deepak, Blumenthal, Sarah R., Kurtser, Iren, Patnaik, Debasis, Gaisina, Irina, Bishop, Joshua, Sheridan, Steven D., Lalonde, Jasmin, Carr, Steven A., Snyder, Evan Y., Haggarty, Stephen J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7039883/ https://www.ncbi.nlm.nih.gov/pubmed/32094324 http://dx.doi.org/10.1038/s41398-020-0753-6 |
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